Research Insights

This section focuses on the most recent research and discoveries across the globe in the various healthcare disciplines.

White matter microstructure disruption associated with PET and cognitive impairment in Alzheimer’s disease

Alzheimers disease AD is associated with regional brain atrophy as well as elevated positron emission tomography PET markers of amyloidbeta eg Fflorbetapir FBP and tau protein

Premature utilization of MRI in the workup of mild hyperprolactinemia

Hyperprolactinemia is a common biochemical finding detected in primary care and guidelines suggest confirmation with a second prolactin measurement to rule out spurious

Helping primary care providers recognize and respond to medication non-adherence and drug-drug interactions: A randomized-controlled clinical utility trial in a value-based care setting

To determine the clinical utility of a novel chronic disease management test among primary care providers practicing in a valuebased care setting The study assessed the ability of primary care providers to recognize

A meta-proteomics approach using autopsy material from the pre-antibiotic era from patients with untreated pulmonary tuberculosis to identify proteins present in early lesions of post-primary tuberculosis

Primary TB and postprimary TB PPTB are different disease entities PPTB occurs only in humans and no animal model mimics the actual pathology of PPTB Information on the immune pathogenesis of PPTB

Disease progression modeling of Alzheimer’s disease based on variational probability principal component analysis

Alzheimers disease AD is a neurodegenerative disorder and the leading cause of dementia Early diagnosis and monitoring of disease progression are crucial for effective intervention

Transcriptomic suppression of immune and ECM stability in skeletal muscle of patients with chronic kidney disease

Chronic kidney disease CKD is a growing public health emergency with a global prevalence of approximately Sarcopenia is a common complication

Patients’ needs and preferences in developing Art-Based Learning in outpatient palliative cancer care: A qualitative study

ArtBased Learning ABL an art pedagogical practice may assist cancer patients by providing a meaningful experience through art viewing However little is known about what needs to be considered when developing an exhibition space for ABL in a palliative care setting

Advanced preclinical testing of a design-optimized ceramic bearing for a cervical total disc replacement

Arthroplasty in the cervical spine is performed using Total Disc Replacement TDR implants This study investigates the safety and tribology of a designoptimized ceramic TDR bearing

Estimating post-operative complication rates in patients with primary brain tumours from routine administrative data: A national cohort study

Neurosurgery is an important element of brain tumour treatment but carries with it the risk of complications Previous work has defined a narrow set of general postoperative complications which are used

Association between delirium and neutrophil percentage-to-albumin ratio in patients with cervical spinal cord injury: A single-center, retrospective study

Traumatic spinal cord injury SCI can be triggered by even minor trauma in older adults and the prevalence of SCI is increasing as the population ages A study by DeVivo et al in the United States reported