Research Insights

This section focuses on the most recent research and discoveries across the globe in the various healthcare disciplines.

Hemodynamical Consequences And Tolerance Of Sustained Ventricular Tachycardia

Clinical tolerance of sustained monomorphic ventricular tachycardia VT is variable and hemodynamical consequences of VT need to be clarified Although VT rate is involved in hemodynamical tolerance

Functional Screening Of Lysosomal Storage Disorder Genes Identifies Modifiers Of Alpha-synuclein Neurotoxicity

Our screen identifies genetic enhancers of Syninduced progressive locomotor dysfunction including knockdown of fly homologs of GBA and other LSD genes with independent support as PD susceptibility factors from human genetics

Cumulative Postoperative Change In Serum Albumin Levels And Organ Failure After Living-donor Liver Transplantation: A Retrospective Cohort Analysis

Many studies have reported that hypoalbuminemia could be associated with organ failure after liver transplantation However most of them focused on serum albumin levels measured at specific time points and not on the trend of serum albumin change

Role Of Cardiovascular Magnetic Resonance Imaging And Cardiopulmonary Exercise Test In Predicting Composite Clinical Outcomes In Patients With Hypertrophic Cardiomyopathy

We aimed to evaluate the additive value of cardiovascular magnetic resonance imaging CMR and cardiopulmonary exercise test CPET to predict clinical outcomes in patients with HCM We enrolled patients with HCM and normal left ventricular

Efficacy of the Combination of Monoclonal Antibodies Against the Sars-Cov-2 Beta and Delta Variants

The pandemic of severe acute respiratory syndrome coronavirus SARSCoV is currently the biggest healthcare issue worldwide This study aimed to develop a monoclonal antibody against SARSCoV from B cells of recovered COVID patients which might have beneficial therapeutic purposes for COVID patients We successfully generated human monoclonal antibodie...

Impact of Atorvastatin Reload on the Prevention of Contrast-Induced Nephropathy in Patients on Chronic Statin Therapy: A Prospective Randomized Trial

This trial aimed to assess the efficacy of Atorvastatin reloading on the prevention of Contrastinduced nephropathy CIN in patients pretreated with this statin and undergoing coronary catheterization

3D Doppler Ultrasound Imaging of Cerebral Blood Flow for Assessment of Neonatal Hypoxic-Ischemic Brain Injury in Mice

Cerebral blood flow CBF acutely reduces in neonatal hypoxicischemic encephalopathy HIE Clinic studies have reported that severe CBF impairment can predict HIE outcomes in neonates Herein the present study uses a noninvasive D ultrasound imaging approach to evaluate the changes of CBF after HI insult and explores the correlation between CBF alterati...

Relationship Between Postoperative Biomarkers of Neuronal Injury and Postoperative Cognitive Dysfunction: A Meta-Analysis

Early biomarkers are needed to identify patients at risk of developing postoperative cognitive dysfunction POCD Our objective was to determine neuronal injuryrelated biomarkers with predictive values for this condition Six biomarkers S neuronspecific enolase NSE amyloid beta A tau neurofilament light chain and glial fibrillary acidic

Identification of a Novel Path for Cerebrospinal Fluid (Csf) Drainage of the Human Brain

How cerebrospinal fluid CSF drains from the human brain is of paramount importance to cerebral health and physiology Obstructed CSF drainage results in increased intracranial pressure and a predictable cascade of events including dilated cerebral ventricles and ultimately cell death The current and accepted model of CSF drainage

Audit to Prescribing Corticosteroids for Pregnant Ladies before Elective Cesarean Section Delivery at Al-Karak Hospital

This study aimed to assess the adherence to the NICE guidelines for prescribing corticosteroids to pregnant women before elective cesarean section delivery at AlKarak Hospital A retrospective audit was conducted on a group medical records of women who underwent elective cesarean