Research Insights

This section focuses on the most recent research and discoveries across the globe in the various healthcare disciplines.

Use of an extended KDIGO definition to diagnose acute kidney injury in patients with COVID-19: A multinational study using the ISARIC–WHO clinical ch

Acute kidney injury AKI is one of the most common and significant problems in patients with Coronavirus Disease COVID However little is known about the incidence and impact of AKI occurring in the community or early in the hospital admission The traditional Kidney Disease Improving Global Outcomes KDIGO definition can fail to identify patients for...

Brain-based measures of nociception during general anesthesia with remifentanil

Catheter radiofrequency RF ablation for cardiac arrhythmias is a painful procedure Prior work using functional nearinfrared spectroscopy fNIRS in patients under general anesthesia has indicated that ablation results in activity in painrelated cortical regions presumably due to inadequate blockade of afferent nociceptors originating within the cardi...

Effect of glutamate infusion on NT-proBNP after coronary artery bypass grafting in high-risk patients (GLUTAMICS II): A randomized controlled trial

Animal and human data suggest that glutamate can enhance recovery of myocardial metabolism and function after ischemia Nterminal probrain natriuretic peptide NTproBNP reflects myocardial dysfunction after coronary artery bypass surgery CABG We investigated whether glutamate infusion can reduce rises of NTproBNP in moderate to highrisk patients afte...

Antibody responses against SARS-CoV-2 variants induced by four different SARS-CoV-2 vaccines in health care workers in the Netherlands

Emerging and future SARSCoV variants may jeopardize the effectiveness of vaccination campaigns Therefore it is important to know how the different vaccines perform against diverse SARSCoV variants As of March the coronavirus disease COVID pandemic has caused over million confirmed infections